N 1 Naphthyl Ethylene Diamine Dihydrochloride AR/ACS 5g

N-(1-Naphthyl)ethylenediamine dihydrochloride, often abbreviated as NEDA or NEDA dihydrochloride, is an organic compound used as a reagent in analytical chemistry and as a building block in organic synthesis. It is a white to beige or pink powder or crystalline solid. It is known for its ability to form colored azo dyes in the presence of nitrite and other related compounds, making it useful in spectrophotometric and colorimetric assays. Key Properties and Uses:

• Appearance: White to off-white or pale brown crystalline powder. 
• Melting Point: Typically between 194-198C. 
• Solubility: Soluble in hot water. 
• Analytical Applications:
  • Griess Reagent: NEDA is a key component of the Griess reagent, used to detect nitrite ions (and other related compounds like nitrate after reduction). 
  • Sulfonamide Determination: It can be used to determine sulfonamides in blood and other samples. 
  • Thiols, Amines, and Phenols: It acts as a coupling agent in the spectrophotometric analysis of thiols, aromatic amines, and aminophenols. 
• Organic Synthesis: Used as a building block in the synthesis of various organic compounds. 
• Fluorescent Probe: Can be used as a highly selective organic fluorescent probe for azide ions. 
• Coordination Chemistry: It can act as a bidentate ligand, forming coordination compounds with certain metal ions. 
• Diazotization: NEDA can undergo diazotization reactions, similar to naphthylamines. 

Safety Information:

• Irritant: NEDA is known to cause skin and eye irritation. 
• Handling: Appropriate personal protective equipment (gloves, eye protection) should be used when handling this chemical. 
• Storage: Store in a cool, dry place, away from incompatible materials. 

In essence, N-(1-Naphthyl)ethylenediamine dihydrochloride is a versatile chemical compound with applications in both analytical chemistry and organic synthesis, particularly in methods involving color development and reactions with aromatic amines and related compounds.