Colistin (Methane Sulphonate) CL 10 mcg

Colistin (Methane Sulphonate) CL 10 mcg Specification

CAS No

Properties
Colistin (Methanesulfonate) CL 10 mcg is a filter paper disc containing 10 micrograms of colistin methanesulfonate, used for antimicrobial susceptibility testing. It helps determine the effectiveness of colistin against bacterial cultures, guiding antibiotic therapy. The disc is typically used in the Kirby-Bauer method. Description: Size: 6 mm diameter Printing: "CL 10" printed on both sides Purpose: Used to determine antibiotic sensitivity of bacteria Mechanism: Colistin methanesulfonate disrupts the cell membrane of gram-negative bacteria, leading to bactericidal effects. Intended Use:Antimicrobial Susceptibility Testing (AST) of bacterial cultures, Assessing bacterial sensitivity to colistin, and Guiding appropriate antibiotic treatment. Key Features: Colistin is a cationic lipopeptide antibiotic with a broad spectrum against gram-negative bacteria. Colistin methanesulfonate is a prodrug that, when hydrolyzed, releases active colistin. The CL 10 mcg disc allows for easy identification and standardized testing.

Usage
Laboratory use

Physical Form
Other

Storage
Freezer

Product Type
Regular

Colistin (Methane Sulphonate) CL 10 mcg Trade Information

Minimum Order Quantity
1 Piece

Payment Terms
Cash in Advance (CID), Days after Acceptance (DA), Cash Advance (CA)

Supply Ability
10 Pieces Per Day

Delivery Time
1 Days

Sample Available
Yes

Packaging Details
Plastic Bottle

Main Export Market(s)
North America, Western Europe, Middle East, Africa, South America, Eastern Europe, Asia, Australia, Central America

Main Domestic Market
All India

Certifications
Himedia

About Colistin (Methane Sulphonate) CL 10 mcg

Colistin (Methanesulfonate) CL 10 mcg is a filter paper disc containing 10 micrograms of colistin methanesulfonate, used for antimicrobial susceptibility testing.It helps determine the effectiveness of colistin against bacterial cultures, guiding antibiotic therapy.The disc is typically used in the Kirby-Bauer method.Description:

Size:6 mm diameter
Printing:"CL 10" printed on both sides
Purpose:Used to determine antibiotic sensitivity of bacteria
Mechanism:Colistin methanesulfonate disrupts the cell membrane of gram-negative bacteria, leading to bactericidal effects.

Intended Use:Antimicrobial Susceptibility Testing (AST) of bacterial cultures, Assessing bacterial sensitivity to colistin, and Guiding appropriate antibiotic treatment.Key Features:

Colistin is a cationic lipopeptide antibiotic with a broad spectrum against gram-negative bacteria.
Colistin methanesulfonate is a prodrug that, when hydrolyzed, releases active colistin.
The CL 10 mcg disc allows for easy identification and standardized testing.

Reliable Antimicrobial Susceptibility Testing

Colistin (Methanesulfonate) CL 10 mcg discs help laboratories accurately assess bacterial sensitivity to colistin. This precision is essential for clinicians to select the most effective antibiotic therapy for infections caused by gram-negative bacteria, supporting patient recovery and antimicrobial stewardship.

Standardized and Easy to Use

Each filter paper disc measures 6 mm and is imprinted with "CL 10" on both sides for easy identification. The standardized 10 mcg dosage ensures consistency across tests, making them suitable for routine use in clinical and research laboratories using the Kirby-Bauer method.

Powerful Mechanism of Action

Colistin methanesulfonate, a prodrug, disrupts the cell membranes of gram-negative bacteria, resulting in bactericidal activity. This mechanism is effective even against resistant bacterial strains, reinforcing its value in critical antimicrobial testing.

FAQ's of Colistin (Methane Sulphonate) CL 10 mcg:

Q: How is the Colistin (Methanesulfonate) CL 10 mcg disc used in antimicrobial testing?

A: The disc is placed on an agar plate inoculated with a bacterial culture as part of the Kirby-Bauer disk diffusion method. After incubation, the zone of inhibition around the disc indicates the microorganism's sensitivity to colistin, guiding antibiotic selection.

Q: What bacteria can be tested with the CL 10 mcg colistin disc?

A: This disc is primarily used to assess the susceptibility of gram-negative bacteria, particularly multidrug-resistant strains, to colistin. It is widely used for organisms like Pseudomonas aeruginosa, Acinetobacter baumannii, and certain Enterobacteriaceae.

Q: When should I use the Colistin (Methanesulfonate) CL 10 mcg discs in the laboratory?

A: These discs are appropriate whenever laboratory personnel need to determine the susceptibility of bacterial isolates to colistin. Their use is recommended in clinical diagnostics as well as routine monitoring of resistance patterns.

Q: Where should Colistin CL 10 mcg discs be stored?

A: The discs should be stored in a freezer to maintain their stability and efficacy. Proper storage ensures reliable performance during susceptibility tests.

Q: What process does the disc use to demonstrate bacterial sensitivity?

A: Colistin methanesulfonate on the disc is released into the surrounding medium, where it is hydrolyzed into active colistin. This active compound disrupts the outer membrane of gram-negative bacteria, inhibiting growth in susceptible strains.

Q: What are the main advantages of using Colistin (Methanesulfonate) CL 10 mcg discs?

A: These discs offer a standardized, easy-to-use method for determining bacterial sensitivity to colistin. Their reliable and objective results are essential for guiding effective antibiotic therapy, especially in cases involving antibiotic-resistant infections.

Tell us about your requirement